November 30, 2023 8 min read

Are you worried your furry friend's stress levels are too high? Recent studies suggest CBD may help manage cortisol, the stress hormone, in dogs. 

Our blog dives into how this natural remedy could calm your pup and offer a healthier lifestyle.

Keep reading to unleash the potential of CBD for your dog's well-being!

Key Takeaways

  • CBD interacts with the endocannabinoid system in dogs, helping to regulate cortisol levels and alleviate stress and anxiety symptoms associated with conditions like Cushing's Disease.
  • Real-world evidence suggests that CBD effectively lowers cortisol levels in dogs, leading to behavioral improvements, reduced inflammation-related discomfort, and an overall sense of well-being for pets.
  • When choosing CBD products for your dog, prioritize safety by opting for high - quality brands that offer transparent information about their product's safety profile and undergo rigorous testing. Additionally, consult with a veterinarian knowledgeable about CBD for dogs to ensure appropriate usage and dosage.

The Connection Between CBD and Cortisol

cbd droplet

CBD interacts with the endocannabinoid system, which plays a crucial role in regulating stress and the release of cortisol in the body.

The stress response and its impacts

Just like humans, dogs experience stress which can lead to elevated cortisol levels. This hormone, often called the 'stress hormone,' increases when your dog feels anxious or is placed in a stressful situation.

High cortisol can have various effects on your dog's body, impacting their immune system and potentially leading to conditions like Cushing's Disease. Chronic stress isn't only uncomfortable for your furry friend; it can also weaken their health over time.

Prolonged exposure to high cortisol can cause hormonal imbalances in dogs, which might contribute to weight gain, loss of energy, and erratic behaviors. These signs may not be immediately apparent but gradually emerge as stress takes its toll on your pet's wellbeing.

Just as worry wears down people over time, long-term stress does the same to dogs by triggering inflammation and other harmful processes within their bodies that could escalate into more serious health issues if left unaddressed.

Endocannabinoid system and stress regulation

Dogs have a special network in their bodies known as the endocannabinoid system (ECS), much like humans do. This complex system plays a key role in regulating stress and keeping everything balanced internally, which can affect how your furry friend feels on any given day.

The ECS works with receptors scattered throughout the body to manageanxiety levels and help maintain calm.

CBD interacts with this vital system by supporting these natural processes. It helps bolster the ECS's ability to regulate hormones like cortisol, often referred to as the "stress hormone." For dogs dealing with conditions like Cushing's Disease where hormonal imbalance is an issue, CBD oil could be a valuable aid in restoring equilibrium and easing anxiety-related symptoms without resorting to harsh medications or therapies.

The Effects of CBD on Cortisol Levels 

happy family with golden retriever

CBD has shown real-world evidence of effectively lowering cortisol levels in dogs, with a mechanism of action that promotes stress regulation and reduction.

Real-world evidence of CBD's effectiveness

Dog owners like you have seen real changes in their pets' stress levels after using CBD oil ortreats. Many report that their dogs, once anxious or struggling with symptoms of Cushing's Disease, are now calmer and more relaxed.

These observations echo findings that suggest CBD may help moderate cortisol, the stress hormone, offering a sense of balance to dogs dealing with hormonal imbalances.

In cases where pups faced chronic conditions such as canine tumors or severe anxiety, including separation anxiety, pet parents have turned to THC-free CBD solutions. They've noticed not just behavioral improvements but also a decrease in inflammation-related discomfort, leading to better overall wellness for their furry friends.

This hands-on experience underlines the potential therapeutic benefits of CBD for managing various health challenges in dogs.

Mechanism of action

CBD interacts with the endocannabinoid system in your dog's body, helping to regulate stress and anxiety. When your dog ingests CBD, it binds to receptors in their brain and immune cells, modulating their response to cortisol.

This interaction helps reduce the release of cortisol, effectively lowering stress levels in your furry friend. Moreover, CBD may also influence serotonin receptors, contributing to a calming effect on dogs struggling with Cushing's Disease or anxiety.

By targeting the endocannabinoid system and affecting cortisol levels, CBD offers a natural way to manage hormonal imbalance and alleviate symptoms related to stress and anxiety in dogs.

Safety, tolerability, and pharmacokinetics

When considering CBD for your dog, it's essential to prioritize safety and tolerability. High-quality CBD products are crucial in ensuring that your dog does not experience any adverse effects.

Additionally, understanding the pharmacokinetics of CBD can help you make informed decisions about dosage and administration. Consulting with a veterinarian who is knowledgeable about CBD for dogs can provide valuable guidance on safety, tolerability, and appropriate usage.

Choosing reputable brands that offer transparent information about their product's safety profile and undergo rigorous testing can give you peace of mind when using CBD for your dog.

Potential Benefits of CBD

happy dog on the beach

CBD has shown promise in reducing cortisol levels and improving management of stress and anxiety in dogs with Cushing's Disease.

Reduction of cortisol levels

CBD lowers cortisol levels in dogs, reducing the stress and anxiety they experience. This natural compound interacts with the endocannabinoid system to help regulate cortisol production, promoting a calmer state of mind for your pet.

By incorporating CBD into your dog's wellness routine, you can support healthy hormonal balance and alleviate symptoms associated with conditions such as Cushing's Disease.

Excessive cortisol can have detrimental effects on your dog's well-being, leading to issues like excessive thirst and urination, muscle weakness, and a pot-bellied appearance. By using CBD to lower cortisol levels in your dog, you can potentially mitigate these symptoms while promoting a better quality of life for your furry friend.

Improved management of stress and anxiety

CBD lowers cortisol levels and helps withstress and anxiety in dogs. It regulates hormone balance, reducing the symptoms of Cushing's Disease as it eases overall discomfort. Full-spectrum CBD oil has calming effects for anxious dogs, aiding in separation anxiety and promoting a sense of well-being.

Dogs benefit from THC-free CBD to alleviate stress without unwanted psychoactive effects. Introducing holistic pet care through natural remedies like CBD offers a promising way to improve your dog’s wellness.

CBD's Role in Managing Stress and Hormonal Balance in Dogs

 When considering the health of dogs in relation to stress, it's essential to focus on the roles of blood pressure and adrenal glands. The adrenal glands are responsible for producing cortisol, a hormone crucial in the body's response to stress.

In stressful situations, these glands release cortisol, which can lead to an increase in blood pressure. This natural response is necessary, but problems arise when cortisol levels fail to regulate properly, potentially leading to conditions like high blood pressure.

Dogs have naturally occurring cannabinoid receptors in their bodies, part of the endocannabinoid system. This system plays a significant role in regulating the nervous system and the body's stress response.

The interaction between CBD and the endocannabinoid system might be particularly relevant in managing conditions like social anxiety disorder in dogs. CBD's potential to interact with cannabinoid receptors may support the nervous system in maintaining balance during stressful situations.

CBD's role in stress management is an area of growing interest. By interacting with the endocannabinoid system, CBD might help regulate the body's stress response, including managing cortisol secretion by the adrenal glands. Excessive or prolonged stress can disrupt this balance, leading to health issues impacting both the nervous system and blood pressure.

For pets with conditions that affect their ability to manage stress, such as social anxiety disorder, CBD may offer support. By potentially influencing the naturally occurring cannabinoid receptors, CBD could help modulate the body's stress response, contributing to more effective stress management.

This is especially important in scenarios where cortisol levels are imbalanced, as prolonged stress can adversely affect both physical and mental health in dogs.

In summary, while CBD shows promise in aiding stress management and potentially influencing factors like blood pressure and cortisol production, it's important for pet owners to approach its use cautiously.

Consulting with a veterinarian is vital to ensure that any supplement, including CBD, is safe and appropriate for their pet, especially when dealing with conditions affecting the nervous system or adrenal glands. This holistic approach can support the well-being of dogs, helping them to lead healthier, more balanced lives.

Where to Find Reliable CBD Products for Your Dog

Look for high-quality CBD products for your dog at trusted online retailers, local pet stores, or through recommendations from fellow dog owners. Always choose THC-free CBD products that are specifically formulated for canine use and made by reputable brands known for their commitment to pet wellness.

Choosing high-quality brands

When choosing high-quality CBD brands for your dog, look for products that are organic and free from pesticides, herbicides, and other harmful chemicals.

  1. Seek out brands that use third - party testing to ensure potency and purity of their CBD products.
  2. Consider the extraction method used by the brand to ensure it's safe and doesn't leave harmful residues in the final product.
  3. Look for CBD products specifically formulated for dogs, as they may have different flavorings or concentrations suited to canine consumption.
  4. Check for transparent labeling that provides insight into the ingredients and CBD concentration in the product.
  5. Read customer reviews and testimonials to gauge the effectiveness of the brand's CBD products for managing stress and anxiety in dogs.

Contact information and resources for purchasing CBD

If you're looking for reliable CBD products for your dog, here are some reputable sources to consider:

  1. Your veterinarian: Your vet can provide guidance on the best CBD products for your dog's specific needs and health conditions.
  2. Online retailers: Look for reputable online stores that specialize in pet CBD products, such asKing Kanine.
  3. Local pet stores: Some pet stores carry a selection of high-quality CBD products for dogs. Be sure to ask about the sourcing and testing of the products they offer.
  4. CBD companies' websites: Many CBD companies have their own websites where you can purchase their products directly, ensuring you're getting authentic and safe products.
  5. Pet community recommendations:Reach out to other dog owners or join online forums and social media groups dedicated to pet health to get recommendations from fellow dog lovers.


In conclusion, CBD has the potential to lower cortisol levels in dogs. This natural remedy may help manage stress and anxiety in our furry friends. With further research and understanding, CBD could offer a promising solution for canine hormonal imbalance and overall well-being.


1. Can CBD oil help dogs with high cortisol levels?

CBD oil for dogs might calm their stress and could balance hormones, which may help manage cortisol levels in dogs with conditions like Cushing's Disease.

2. What are the benefits of using THC-free CBD for my dog?

THC-free CBD is safe for dogs and can have calming effects, reducing anxiety without causing any psychoactive responses, especially in those with Cushing's or other hormonal imbalances.

3. Will using CBD ease my dog’s symptoms of Cushing’s Disease?

CBD has therapeutic benefits that could assist in managing symptoms of Cushing's Disease by possibly lowering inflammation and aiding to regulate hormones in your furry friend.

4. Is full spectrum CBD oil better for a dog with hormonal issues like Cushing's Disease?

Full-spectrum CBD oil contains various natural compounds that might work together to enhance its stress-reduction and anti-inflammatory properties beneficial for dogs dealing with hormonal imbalances from diseases such as Cushing’s.

5. Should I consider euthanizing my dog if they have Cushing’s or can CBD help?

Before considering such a significant decision, it's worth exploring options like using therapeutic-grade cannabidiol (CBD) which could offer relief from symptoms associated with canine tumors and contribute positively to overall dog health.